Here's a few studies from what I found by googling "could whooping cough mutate?":
"Whooping Cough Is Surging in the U.S."
SUMMARY:
The United States is facing a sharp and deeply concerning resurgence of pertussis, better known as whooping cough, a vaccine-preventable illness that was once nearly eliminated thanks to robust public health efforts.
Published May 5, 2025
LINK:
https://www.nyas.org/ideas-insights/blog/whooping-cough-is-surging-in-the-u-s-what-you-need-to-know/Also,
"Pertussis Surveillance and Trends from CDC"
SUMMARY:
Public Health
Oct. 27, 2025
CDC tracks pertussis cases using a national surveillance system.
CDC works with several states on enhanced pertussis surveillance.
Cases have increased over the last few decades.
Experts believe that much of the disease goes unrecognized and unreported.
Learn where the data come from and latest trends.
LINK:
https://www.cdc.gov/pertussis/php/surveillance/index.htmlAnd,
"Sweet targets: the quest for an improved whooping cough vaccine
By Connor Yeck | Aug 26, 2025"
SUMMARY:
Researchers are aiming to develop a “one-two punch” vaccine strategy against pertussis, more commonly known as whooping cough. This work could ultimately help reduce transmission of the disease and combat the threat of resistant bacteria mutating into stronger, more lethal “superbugs.”
LINK:
https://www.chemistry.msu.edu/news/2025-8-sweet-targets-huang.aspx