Data Report
Covid19 => Covid Support => Topic started by: gv_twiitterpated on January 07, 2025, 05:45:52 pm
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Metformin is a diabetes drug that has shown to be an effective antiviral and Long-Covid preventative in patients with an active Covid infection. Here is some of the data I've compiled with regards to efficacy, dosing, and access:
Basic Overview from the NIH (https://ncats.nih.gov/news-events/news/can-metformin-treat-COVID-19-and-prevent-long-COVID-NCATS-and-partners-pursue-answers)
Studies:
Favorable Antiviral Effect of Metformin on SARS-CoV-2 Viral Load in a Randomized, Placebo-Controlled Clinical Trial of COVID-19 (https://academic.oup.com/cid/article/79/2/354/7660393)
Articles re above study: "U of M study finds metformin reduces COVID-19 viral load, viral rebound" (https://med.umn.edu/news/u-m-study-finds-metformin-reduces-covid-19-viral-load-viral-rebound), Study from former KL2 scholar finds metformin reduces COVID-19 viral load, viral rebound (https://ctsi.umn.edu/news/study-former-kl2-scholar-finds-metformin-reduces-covid-19-viral-load-viral-rebound)
Outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months (https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00299-2/fulltext)
Metformin is a potential therapeutic for COVID-19/LUAD by regulating glucose metabolism (https://www.nature.com/articles/s41598-024-63081-0)
Usage:
ZeroCovidCommunity subreddit thread on immediate-release vs extended-release metformin (https://www.reddit.com/r/ZeroCovidCommunity/comments/1gtw0gr/notes_on_metformin_and_long_covid_immediate_vs/)
ZCC subreddit thread inviting information-sharing on the possible benefit of long-term metformin usage as a preventative for LongCovid (https://www.reddit.com/r/ZeroCovidCommunity/comments/1fkxego/metformin_as_prevention/)
Access:
ZCC subreddit thread on how to acquire metformin via AgelessRx (https://www.reddit.com/r/ZeroCovidCommunity/comments/1hmrkqk/getting_metformin_from_agelessrx/)
ZCC subreddit thread on where/how to acquire paxlovid and metformin in advance (https://www.reddit.com/r/ZeroCovidCommunity/comments/1h7e37j/zcc_doctors_willing_to_presecribe/) (see comment section)
ZCC subreddit recommending acquiring paxlovid and metformin ahead of an infection (https://www.reddit.com/r/ZeroCovidCommunity/comments/1hi8prg/prepare_for_a_covid_infection_metformin/), with tips on where and how-to